DEX‐Induced SREBF1 Promotes BMSCs Differentiation into Adipocytes to Attract and Protect Residual T‐Cell Acute Lymphoblastic Leukemia Cells After Chemotherapy (Adv. Sci. 19/2023)
نویسندگان
چکیده
T-Cell Acute Lym-phoblastic Leukemia In article number 2205854, Jingjing Ye, Min Ji, Chunyan and co-workers observed aberrant adipogenesis in the bone marrow of chemotherapy-treated T-cell acute lymphoblastic leukemia (T-ALL) patients, differentiated-adipocytes attract support residual T-ALL cells. Last, an SREBF1 inhibitor demonstrates superior improvement on therapeutic effect dexamethason by reducing provides a feasible strategy to solve dilemma recurrence.
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ژورنال
عنوان ژورنال: Advanced Science
سال: 2023
ISSN: ['2198-3844']
DOI: https://doi.org/10.1002/advs.202370125